The Removal of Hydrogel Explants

With apologies from the authors, the publication titled “Twice-Daily Brinzolamide/Brimonidine Fixed Combination versus Brinzolamide or Brimonidine in Open-Angle Glaucoma or Ocular Hypertension,” (Ophthalmology 2014;121:2348-55) had an error.

A 72-year-old man presented with an 8-year history of an enlarging conjunctival mass with several large temporal feeder vessels in the right eye (Fig 1, arrow). Excision was performed and histopathology revealed squamous cell carcinoma (Hematoxylin & Eosin, Figs 2 and 3) with dyskeratosis (star), mitotic figures, apoptotic bodies (arrow), full thickness atypia, pleomorphism, and keratin pearls (asterisk). The patient was started on Interferon alfa 2b therapy to prevent recurrence.

A 51-year-old man presented with a 10-year history of a gradually enlarging, asymptomatic, left medial canthus mass (Fig 1). Hematoxylin and eosin stain of the excised lesion revealed hyperplastic sebaceous glands forming irregular-shaped lobules with lumina containing proteinaceous material (asterisks) consistent with sebaceous adenoma (Figs 2 and 3). Although this patient was found to be otherwise healthy, a solitary sebaceous adenoma may be associated with malignancies of the gastrointestinal tract or other viscera (Muir-Torre syndrome).