In an analysis from the second year of the Comparison of Age-related Macular Degeneration Treatments Trials (CATT), Sharma et al (p. 865) described the association between visual acuity (VA) and morphologic features on fundus photography (FP), fluorescein angiography (FA), and optical coherence tomography (OCT). They found that the associations between VA and morphologic features that were identified during year 1 of this prospective, randomized study were maintained or strengthened during year 2.