Recent advances in ultra-widefield imaging that allow generation of high-definition, 3-dimensional representations of the fundus are redefining our approach to quantification of retinal diseases. The clinical relevance of these advances as illustrated by Sagong et al in their article entitled, “Assessment of Accuracy and Precision of Quantification of Ultra-widefield Images” is in establishing the tools required to define retinal pathology.1,2 Ideally, for a new metric to carry substantial value, it would facilitate ≥1 of the following criteria: meaningful quantification of disease severity, prediction of disease progression, and/or prediction of treatment response.
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