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We thank Pautler and Browning for their interest and comments regarding our recent article. The suggestions of Pautler and Browning are interesting, but we do not think that uveal effusion is the underlying cause of the cystoid fluid collections (CFCs) in dominant cystoid macular dystrophy (DCMD). The phenotype is different from the case report of Pautler and Browning1: in DCMD, we observed a very constant, autosomal-dominantly inherited, early-onset phenotype starting with intraretinal CFCs diffusely affecting the posterior pole without persistent serous subretinal fluid, without choroidal folds.
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A 60-year-old woman with a subretinal Artificial Silicon Retina microchip (Optobionics, Inc., Glen Ellyn, IL) that had been implanted 10 years previously. No encapsulation, neovascularization, or inflammatory response was noted.
Read more: Ten-year Follow-Up of a Subretinal Silicon Prosthesis for Retinitis Pigmentosa
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In a perfect world, how would the peer review process work to ensure that the latest, highest quality scientific research is conveyed to busy practitioners who are eager to provide the best care for their patients? Authors would conduct hypothesis-driven investigations on important clinical questions about which they have no conflict of interest. They would describe their findings in clear, concise prose; cite appropriate (but not excessive) references to previous work; and use plagiarism detection software to ensure that their paper does not contain text that previously has been published.
Read more: Just Because It's Published Doesn't Mean It's Perfect
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A 31-year-old woman developed bilateral painless enlargement of the lacrimal glands over a 2-month period (Figs 1 and 2, arrows). She underwent a right orbitotomy with lacrimal gland biopsy, which showed marked non-caseating granulomatous inflammation (Fig 3, star) displacing the normal gland architecture. Multinucleated giant cells were also present (Fig 4, arrow).
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I have read with great interest this brief report claiming the universal recommendation for Age-Related Eye Disease Study (AREDS) supplements.1 Because this recommendation is of substantial importance to public health, affects tens of millions of patients, and is mandated by a Physician Quality Reporting System (PQRS) measure, the issue deserves further scrutiny.