The latest clinical breakthroughs, practice management updates, and national advocacy alerts directly from the American Academy of Ophthalmology.
Pilomatrixoma: An Uncommon Tumor of the Brow
A 32-year-old man presented with a mass of the left upper brow, which enlarged over 8 weeks (Fig 1, black arrow). After surgical removal, it was found to be a pilomatrixoma (or calcifying epithelioma of Malherbe; Fig 2). Pilomatrixomas are rare (<1% of all benign skin tumors), and believed to be caused by genetic alterations in hair cells causing dysregulated apoptosis. Their histology is striking: darkly staining “basophilic” cells (Fig 3, arrow), shadow cells lacking nuclei (Fig 3, asterisks), keratinization (Fig 3, star), and calcium deposits.
We extend our deepest gratitude to our Platinum, Gold, and Silver partners. Your generous support fuels our mission to advance medical education, advocate for patient safety, and foster breakthrough innovations across West Virginia.