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The latest clinical breakthroughs, practice management updates, and national advocacy alerts directly from the American Academy of Ophthalmology.
Subepidermal Calcified Nodule in the Periocular Region: A Report of 6 Cases
Calcinosis cutis is a calcium deposition disorder of the skin that is classically divided into 4 categories including dystrophic, metastatic, iatrogenic, and idiopathic.1,2 Dystrophic calcification develops after localized tissue damage with normal serum calcium and phosphorus levels, whereas metastatic calcification precipitates in tissues from systemic calcium/phosphorus metabolic dysfunction with increased serum calcium levels. Iatrogenic calcification follows local transcutaneous therapy such as intravenous infusion of calcium chloride, calcium gluconate, or other products.
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