The Relationship Between Reticular Pseudodrusen and Severity of AMD

Mimoun et al1 were first to describe a peculiar yellowish pattern in patients with age-related macular degeneration (AMD) as reticular pseudodrusen (RPD) in 1990. Since that time, improved identification and clinical descriptions of RPD and their dynamic nature have become possible with the development of newer imaging modalities including infrared and spectral domain optical coherence tomography (SD OCT) imaging. By most investigators, RPD are considered to be associated with or at least have some developmental relationship to subretinal drusenoid deposits, which have been identified histopathologically as residing internal to the retinal pigment epithelium.