Validated Prediction Model of Depression in Visually Impaired Older Adults

Subthreshold depression is highly prevalent in visually impaired older adults and an important risk factor for major depressive disorder.1 For early diagnosis and treatment, it is important to identify patients who are at high risk of having subthreshold depression. Former research found inconsistent results and prediction models were never validated externally.2 Therefore, the aim of this study was to assess comprehensively potential predictor variables by internally validating a prediction model for subthreshold depression in a European sample and validating this model externally in a comparable Australian sample.