The latest clinical breakthroughs, practice management updates, and national advocacy alerts directly from the American Academy of Ophthalmology.
Whole Exome Profiling of Ocular Surface Squamous Neoplasia
Ocular surface squamous neoplasia (OSSN) represents a spectrum of diseases ranging from mild dysplasia to invasive squamous cell carcinoma. Ocular surface squamous neoplasia can be successfully managed with surgical excision or medical therapy. Interferon-α-2b (IFNα-2b) treatment recently has been established as a standard treatment option for OSSN, eliminating the need for surgical excision. However, approximately 15% of tumors do not respond to IFNα-2b therapy.1 It remains unclear which tumor-specific factors may affect treatment response or course after treatment.
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