Recent advances in ultra-widefield imaging that allow generation of high-definition, 3-dimensional representations of the fundus are redefining our approach to quantification of retinal diseases. The clinical relevance of these advances as illustrated by Sagong et al in their article entitled, “Assessment of Accuracy and Precision of Quantification of Ultra-widefield Images” is in establishing the tools required to define retinal pathology.1,2 Ideally, for a new metric to carry substantial value, it would facilitate ≥1 of the following criteria: meaningful quantification of disease severity, prediction of disease progression, and/or prediction of treatment response.

To review the available evidence on the effectiveness of prophylactic topical nonsteroidal anti-inflammatory drugs (NSAIDs) in preventing vision loss resulting from cystoid macular edema (CME) after cataract surgery.

Orbital inflammatory diseases (OIDs) from various causes may have a similar clinical presentation, with orbital biopsy being a key investigation to assist with diagnosis. Granulomatosis with polyangiitis (GPA) is an idiopathic granulomatous inflammatory disease that forms part of the spectrum of antineutrophil cytoplasm antibody (ANCA)-associated vasculitis. When left untreated, GPA is an aggressive disease, can result in severe, permanent organ damage, and is potentially life threatening when vital organs are affected.

Retinal vasoproliferative tumor (VPT) describes a vascular nodular tumor arising in the neurosensory retina with associated telangiectasia, lipid exudation, and subretinal fluid. These tumors may occur sporadically (80%) or secondary to other intraocular pathology, such as uveitis, retinitis pigmentosa, toxoplasmosis, toxocariasis, vitreoretinal surgery, familial exudative vitreoretinopathy, Sickle cell disease, retinopathy of prematurity, Coat's disease, Waardenburg's syndrome, and neurofibromatosis type 1.

With the introduction of enhanced depth imaging optical coherence tomography (OCT), there have been a few studies investigating interocular differences in choroidal thickness.1–4 Previous studies have demonstrated interocular symmetry of choroidal thickness, and interocular difference seems to be correlated with interocular difference of axial length in adults1,2 and children.3

Toxoplasmic retinochoroiditis is a clinical diagnosis which may be supported by positive serum immunoglobulin (Ig)M and/or IgG titers. Classically, it is manifested by necrotizing retinitis with secondary involvement of the choroid and vitreous.1