AAO News
The latest clinical breakthroughs, practice management updates, and national advocacy alerts directly from the American Academy of Ophthalmology.
To analyze the value of novel measures of retinal pigment epithelium–drusen complex (RPEDC) volume to predict 2-year disease progression of intermediate age-related macular degeneration (AMD).
Eyegate Pharmaceuticals announced promising interim data showing iontophoresis can non-invasively deliver dexamethasone phosphate to the posterior segment.
The authors of this randomized trialfound that neither cataract surgery nor IOL type have a significant impact on circadian photoentrainment or sleep quality.
Allergan announced it will develop and commercialize dry eye drug tavilermide through an exclusive licensing agreement with Mimetogen Pharmaceuticals.
Researchers have identified a steroid that has the potential to reverse cataracts by blocking α-crystallin aggregation.
CACNA2D4 (NM_172364) encodes the α2δ4 subunit of the photoreceptor voltage-gated calcium channels (Cav1.4), which modulate glutamate release from the photoreceptors to the bipolar cells.1 CACNA2D4 mutations have been associated with a rare recessive retinal cone dystrophy (RCD4, OMIM #610478),2 first described in 2 adult siblings with a homozygous truncating mutation in exon 25 of CACNA2D4: c.[2406C>A] (p.[Tyr802*]) associated with mildly reduced visual acuity (VA), photophobia, foveal pigment mottling, an electronegative scotopic electroretinogram (ERG) and markedly subnormal cone responses.
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