We thank Drs Takkar and Azad for their interest in our work.1 They propose a novel concept, that choroidal detachment resulting from retinal detachment could itself damage the ciliary nerves, and that this may be a frequent occurrence. According to most series, however, including the one Takkar and Azad refer to (citation 2 in their letter), choroidal detachment, noted generally to occur in approximately 4% of patients, is a rather infrequent finding, secondary to very low intraocular pressures that may be associated with chronic retinal detachments, the majority of those aphakic.

Formycon is solidifying its position in ophthalmologic follow-on products with the development of a biosimilar for aflibercept. It joins the follow-on version of ranibizumab that is already in Phase 3 clinical trials.

Using a new low-vision assessment tool developed specifically for patients implanted with retinal prostheses, investigators showed that Second Sight's Argus II improves the ability of blind individuals to perform everyday tasks.

The Triggerfish contact lens has a built-in sensor that could help identify patients at higher risk of glaucoma progression.

The potential for eyes after cataract surgery to have an increased risk of progression of age-related macular degeneration (AMD) has long been of concern.1 We previously reported 3-year follow-up findings from the Australian Cataract Surgery and Age-related Macular Degeneration (CSAMD) study showing no increased incidence of early or late AMD in eyes 3 years after surgery, compared with nonoperated fellow eyes of the same patients.2 A recent 20-year follow-up report from the Beaver Dam Eye Study (BDES) once again confirmed that cataract surgery was associated with an increased incidence of late but not early AMD over the long-term.

To elucidate the functional effect of the ABCA4 variant c.5461-10T→C, one of the most frequent variants associated with Stargardt disease (STGD1).